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Published: 17 Mar 2026, 03:27 UTC
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Eli Lilly's (LLY) orforglipron achieved the primary and all key secondary end...

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Eli Lilly's (LLY) orforglipron achieved the primary and all key secondary end...

** Eli Lilly's (LLY) orforglipron achieved the primary and all key secondary endpoints for weight maintenance vs. placebo at 52 weeks following weight loss on Wegovy or Zepbound.**


  • Eli Lilly has submitted orforglipron to the FDA for obesity treatment.
  • The drug demonstrated weight maintenance success in a Phase 3 trial.
  • Market participants are observing potential impacts on the pharmaceutical sector.


Eli Lilly has taken a significant step in the obesity treatment market by submitting its oral drug, orforglipron, to the U.S. Food and Drug Administration (FDA). This submission follows a successful Phase 3 trial where orforglipron met its weight maintenance goals compared to a placebo after 52 weeks. The trial involved patients who had previously achieved weight loss using injectable incretins such as Wegovy or Zepbound.


The pharmaceutical sector is closely monitoring this development, as the approval of orforglipron could potentially reshape the obesity treatment landscape. Eli Lilly's move to introduce an oral GLP-1 therapy could offer a more convenient alternative to injectable treatments, potentially expanding the market reach and patient compliance.


Market participants are discussing the implications for Eli Lilly's stock (LLY), as the approval of orforglipron could enhance the company's competitive position in the obesity treatment market. The drug's success in clinical trials may also influence investor sentiment towards other companies developing similar therapies, such as Novo Nordisk, which markets Wegovy.


The broader pharmaceutical sector could see shifts in market dynamics, with companies focusing on obesity treatments potentially gaining increased attention. ETFs that track the healthcare sector, such as the Health Care Select Sector SPDR Fund (XLV), may also be influenced by these developments, as investors assess the potential impact of new drug approvals on the sector's performance.


In the context of the current market environment, where healthcare innovation remains a focal point, the submission of orforglipron to the FDA highlights the ongoing advancements in obesity treatment options. Analysts note that traders are watching for regulatory updates and potential competitive responses from other pharmaceutical companies.


Trader Insight:


  • Some traders may consider monitoring Eli Lilly's stock (LLY) for potential movements following the FDA submission.
  • Market participants are observing the Health Care Select Sector SPDR Fund (XLV) for broader sector impacts.
  • Analysts note that traders are watching Novo Nordisk's stock (NVO) for competitive positioning in the obesity treatment market.


Disclaimer: This is not trading advice. For informational purposes only.

#Eli Lilly & Co#LLY.US#US Equities#LLY#Pharmaceuticals#Pharmaceuticals (Group)#Pharmaceuticals, Biotechnology & Life Sciences#Eli Lilly and Co#Equities#S&P 500 Index#Important#EU Session
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Apple Inc

AAPLNASDAQ NMS - GLOBAL MARKET
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$254.10-1.53(-0.60%)

Last updated: 4/2/2026, 4:28:00 PM

Market Cap

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** Eli Lilly's (LLY) orforglipron achieved the primary and all key secondary endpoints for weight maintenance vs....

Equities

newsquawk_1b7932eb-6c16-4634-8789-24adc7fe4cca_63b4dea1.webp
United StatesUSD+14
9 hours ago

"Iran's Judiciary on Protests: We Will Show No Mercy", according to Al Arabiya

"Iran's Judiciary on Protests: We Will Show No Mercy", according to Al Arabiya Iran's Judiciary has vowed no mercy...

United StatesUSD+17

Lockheed Martin (LMT) expects to recognise a non-cash

Lockheed Martin (LMT) expects to recognise a non-cash, non-operating pre-tax settlement charge of approximately...

Newsquawk9 hours ago
EquitiesAsian Session+10

Meta (META) is developing a new AI image and video model codenamed 'Mango'

Meta (META) is developing a new AI image and video model codenamed 'Mango', according to WSJ. Meta is developing a...

Newsquawk9 hours ago
United StatesUSD+18

OpenAI is aiming to raise as much as USD 100bln in fundraising round which co...

OpenAI is aiming to raise as much as USD 100bln in fundraising round which could value it as much as USD 830bln,...

Newsquawk9 hours ago
newsquawk_92919edf-5602-4f43-9643-e30608f80bb0_df226645.webp
United StatesUSD+21

Trump Media and Technology (DJT) says if merger is terminated under certain c...

Trump Media and Technology (DJT) says if merger is terminated under certain conditions, TAE may be obliged to pay...

Newsquawk9 hours ago
newsquawk_ca2c46fa-7010-4191-807f-319d39abd9cd_244b6b68.webp
United StatesUSD+21

Nike (NKE) expects Q3 revenue to decline by low single-digits vs estimates of...

Nike (NKE) expects Q3 revenue to decline by low single-digits vs estimates of a 1.5% drop to USD 11.43bln Nike...

Newsquawk9 hours ago
newsquawk_c4a6e31a-beb9-4e00-8725-3a95dfbd7fb3_5bd2c728.webp
NIKE IncNKE.US+9

Nike (NKE) CEO says dimensions of their businesses are moving at different sp...

Nike (NKE) CEO says dimensions of their businesses are moving at different speeds and recovery will take time,...

Newsquawk9 hours ago
FedEx CorpFDX.US+8

FedEx (FDX) CFO says expects Q3 revenue to be in line with Q2 and expects ope...

FedEx (FDX) CFO says expects Q3 revenue to be in line with Q2 and expects operating expenses to rise in Q3 due to...

Newsquawk9 hours ago
Downer EDI LtdDOW.AT+9

Downer EDI (DOW AT) selected as preferred contractor for NZTA highway contracts

Downer EDI (DOW AT) selected as preferred contractor for NZTA highway contracts, with estimated total revenue from...

Newsquawk9 hours ago
AustraliaSingapore+26

PRE-MARKET TAIWAN AND SINGAPORE STOCKS NEWS: Singapore Telecommunications (ST...

PRE-MARKET TAIWAN AND SINGAPORE STOCKS NEWS: Singapore Telecommunications (ST SP) unit Optus was criticised in...

Newsquawk9 hours ago
United StatesUSD+37

PRE-MARKET CHINESE STOCKS NEWS: TikTok has signed a deal to sell its US entit...

PRE-MARKET CHINESE STOCKS NEWS: TikTok (?? CH) has signed a deal to sell its US entity to a joint venture...

Newsquawk9 hours ago
newsquawk_d7d38c1b-4dd6-4ff3-a7b1-59159f7be72f_9fa901cd.webp
United StatesUSD+25
9 hours ago

US President Trump administration initiates multi-agency review of NVIDIA (NV...

US President Trump administration initiates multi-agency review of NVIDIA (NVDA) H200 licenses for sales to China,...

Phillips 66PSX.US+10

Phillips 66 (PSX) reports emissions event at Sweeney refinery and petrochemic...

Phillips 66 (PSX) reports emissions event at Sweeney refinery and petrochemical complex in Texas on December 17th...

Newsquawk9 hours ago
United StatesUSD+36

PRE-MARKET INDIAN STOCKS NEWS: Bharat Petroleum (BPCL IS) board approved the ...

PRE-MARKET INDIAN STOCKS NEWS: Bharat Petroleum (BPCL IS) board approved the formation of a JV with Coal India...

Newsquawk9 hours ago
United StatesUSD+16

US Homeland Security Secretary Noem says at President Trump's direction

US Homeland Security Secretary Noem says at President Trump's direction, she is immediately directing the USCIS to...

Newsquawk9 hours ago
newsquawk_ed75f8a0-2e0d-4d44-bb68-ff1142c07388_b5dde8b1.webp
Pfizer IncPFE.US+11

Cipla (CIPLA IS) wins exclusive supply and marketing deal for four brands of ...

Cipla (CIPLA IS) wins exclusive supply and marketing deal for four brands of Pfizer (PFE) drugs for five years...

Newsquawk9 hours ago
newsquawk_768599e1-a757-44ee-bf91-40aa51e73fdb_9d9c67bd.webp
Google IncMicrosoft Corp+19

The first phase of a Nanto data centre cluster would have 400-megawatt power ...

The first phase of a Nanto (?? CH) data centre cluster would have 400-megawatt power capacity, which would be...

Newsquawk9 hours ago
newsquawk_d073d6f7-13f6-4c9e-8527-f41c35ed11b9_efdc9311.webp
USDRussian Federation+68

Additional European Equity News

Additional European Equity News Balfour Beatty generates GBP 24mln profit from the sale of Foundry Courtyard. BBVA...

Newsquawk9 hours ago

S&P 500 Index

newsquawk_c90758a9-5b6f-45ea-a61a-0e50b3f46a64_29acbeb4.webp
United StatesUSD+17
9 hours ago

Lockheed Martin (LMT) expects to recognise a non-cash

Lockheed Martin (LMT) expects to recognise a non-cash, non-operating pre-tax settlement charge of approximately...

EquitiesAsian Session+10

Meta (META) is developing a new AI image and video model codenamed 'Mango'

Meta (META) is developing a new AI image and video model codenamed 'Mango', according to WSJ. Meta is developing a...

Newsquawk9 hours ago
United StatesUSD+21

Nike (NKE) expects Q3 revenue to decline by low single-digits vs estimates of...

Nike (NKE) expects Q3 revenue to decline by low single-digits vs estimates of a 1.5% drop to USD 11.43bln Nike...

Newsquawk9 hours ago
NIKE IncNKE.US+9

Nike (NKE) CEO says dimensions of their businesses are moving at different sp...

Nike (NKE) CEO says dimensions of their businesses are moving at different speeds and recovery will take time,...

Newsquawk9 hours ago
newsquawk_aa025598-2945-4fb1-8594-c983ef66f2ab_b0587170.webp
EquitiesAsian Session+9

AIG (AIG) is to form a special purpose vehicle for a strategic partnership wi...

AIG (AIG) is to form a special purpose vehicle for a strategic partnership with Amwins and Blackstone (BX US) and...

Newsquawk9 hours ago
newsquawk_75a3f8bd-5d61-4275-bee9-d6fc002334b2_5fd91a5c.webp
FedEx CorpFDX.US+8

FedEx (FDX) CFO says expects Q3 revenue to be in line with Q2 and expects ope...

FedEx (FDX) CFO says expects Q3 revenue to be in line with Q2 and expects operating expenses to rise in Q3 due to...

Newsquawk9 hours ago
newsquawk_68837f33-89f4-4415-bcf3-92f9e7d862f4_52656401.webp
Downer EDI LtdDOW.AT+9

Downer EDI (DOW AT) selected as preferred contractor for NZTA highway contracts

Downer EDI (DOW AT) selected as preferred contractor for NZTA highway contracts, with estimated total revenue from...

Newsquawk9 hours ago
NXP Semiconductor NVNXPI.US+11

China Commerce Ministry says the Vice Minister met with the General Manager o...

China Commerce Ministry says the Vice Minister met with the General Manager of NXP Semiconductors (NXPI) China...

Newsquawk9 hours ago
United StatesUSD+37

PRE-MARKET CHINESE STOCKS NEWS: TikTok has signed a deal to sell its US entit...

PRE-MARKET CHINESE STOCKS NEWS: TikTok (?? CH) has signed a deal to sell its US entity to a joint venture...

Newsquawk9 hours ago
United StatesUSD+25

US President Trump administration initiates multi-agency review of NVIDIA (NV...

US President Trump administration initiates multi-agency review of NVIDIA (NVDA) H200 licenses for sales to China,...

Newsquawk9 hours ago
United StatesUSD+36

PRE-MARKET INDIAN STOCKS NEWS: Bharat Petroleum (BPCL IS) board approved the ...

PRE-MARKET INDIAN STOCKS NEWS: Bharat Petroleum (BPCL IS) board approved the formation of a JV with Coal India...

Newsquawk9 hours ago
newsquawk_ed75f8a0-2e0d-4d44-bb68-ff1142c07388_b5dde8b1.webp
Pfizer IncPFE.US+11
9 hours ago

Cipla (CIPLA IS) wins exclusive supply and marketing deal for four brands of ...

Cipla (CIPLA IS) wins exclusive supply and marketing deal for four brands of Pfizer (PFE) drugs for five years...

Google IncMicrosoft Corp+19

The first phase of a Nanto data centre cluster would have 400-megawatt power ...

The first phase of a Nanto (?? CH) data centre cluster would have 400-megawatt power capacity, which would be...

Newsquawk9 hours ago
USDRussian Federation+68

Additional European Equity News

Additional European Equity News Balfour Beatty generates GBP 24mln profit from the sale of Foundry Courtyard. BBVA...

Newsquawk9 hours ago
United StatesUSD+10

US ambassador to Israel says the US is not considering supplying Turkey with ...

US ambassador to Israel says the US is not considering supplying Turkey with F-35 jets (LMT), which is not on the...

Newsquawk10 hours ago
newsquawk_9d43c05e-42e7-4ab5-8fc7-8ec2d60514c4_bbccc2fc.webp
United StatesUSD+43

European Movers: Renault (RNO FP) +1.2%

European Movers: Renault (RNO FP) +1.2%, Ipsen (IPN FP) -1.5%, Adidas (ADS GY) -1.8%, Puma (PUM GY) -2.8%, WH...

Newsquawk10 hours ago
newsquawk_94ab80cf-e282-4dbf-aff1-c4c2cd448023_cf52263f.webp
GermanyHong Kong+24

Italy's Competition Authority ends probes of Stellantis (STLAP FP/ STLAM IM)

Italy's Competition Authority ends probes of Stellantis (STLAP FP/ STLAM IM), Volkswagen (VOW3 GY), Tesla (TSLA)...

Newsquawk10 hours ago
newsquawk_06ce4d53-1711-42da-8327-b8d5e5dab8b7_a77361b9.webp
USDSoftware+15

Germany's Competition Authority approves the merger of Palo Alto (PANW) and I...

Germany's Competition Authority approves the merger of Palo Alto (PANW) and Israel's Cyberark (?? CH) software...

Newsquawk10 hours ago

Important

newsquawk_f75b8028-baa7-4bb8-b93a-e0985972fa08_3196a905.webp
Oracle CorpSoftware+10
9 hours ago

TikTok has signed a deal to sell its US entity to a joint venture controlled ...

TikTok has signed a deal to sell its US entity to a joint venture controlled by American investors, according to...

New ZealandImportant+11

New Zealand ANZ Business Outlook* (Dec) 73.6% (Prev. 67.1%)

New Zealand ANZ Business Outlook (Dec) 73.6% (Prev. 67.1%) * Traders are closely monitoring the energy sector amid...

Newsquawk9 hours ago
United StatesUSD+25

US President Trump administration initiates multi-agency review of NVIDIA (NV...

US President Trump administration initiates multi-agency review of NVIDIA (NVDA) H200 licenses for sales to China,...

Newsquawk9 hours ago
JapanData+12

Japanese Finance Minister Katayama says will consider fiscal sustainability t...

Japanese Finance Minister Katayama says will consider fiscal sustainability to some extent in compiling next...

Newsquawk9 hours ago
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Australia & New Zealand Banking GroupANZ.AT+4

Australia's ASIC says federal court orders AUD 250mln combined penalties agai...

Australia's ASIC says federal court orders AUD 250mln combined penalties against ANZ (ANZ AT) Traders are closely...

Newsquawk9 hours ago
newsquawk_2d38852b-ab19-43de-b24d-415a4edafc17_bda11483.webp
EuropeGeopolitical+22

German Chancellor Merz says Ukraine will receive an interest-free loan of EUR...

German Chancellor Merz says Ukraine will receive an interest-free loan of EUR 90bln with these funds sufficient to...

Newsquawk9 hours ago
newsquawk_0865e108-efb3-4fe8-8aff-592922c839de_c7edb373.webp
ImportantAsian Session+1

Bank of Korea announces temporary measures to boost dollar supply in the mark...

Bank of Korea announces temporary measures to boost dollar supply in the market from financial institutions...

Newsquawk9 hours ago
United KingdomImportant+12

UK PSNB Ex Banks GBP (Nov) 11.653B GB vs. Exp. 10.0B GB (Prev. 17.434B GB

UK PSNB Ex Banks GBP (Nov) 11.653B GB vs. Exp. 10.0B GB (Prev. 17.434B GB, Rev. 21.189B GB) Traders are closely...

Newsquawk9 hours ago
GeopoliticalImportant+2

China's Foreign Ministry on Japanese official talking about nuclear arms

China's Foreign Ministry on Japanese official talking about nuclear arms, says if the reports are true, then the...

Newsquawk10 hours ago
ImportantEU Session+2

China's Commerce Ministry has launched an investigation into some rubber prod...

China's Commerce Ministry has launched an investigation into some rubber products from the US, South Korea and the...

Newsquawk10 hours ago
JapanAsia+14

Japanese Economy Minister Kiuchi says FX is affected by various factors

Japanese Economy Minister Kiuchi says FX is affected by various factors, determined at markets Japanese Economy...

Newsquawk10 hours ago
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FrancePrime Minister+3
10 hours ago

French Prime Minister Lecornu says parliament will be unable to vote on a bud...

French Prime Minister Lecornu says parliament will be unable to vote on a budget for France before the end of the...

United StatesUSD+15

US President Trump says "I do not rule out a war with Venezuela", via NBC

US President Trump says "I do not rule out a war with Venezuela", via NBC US President Trump does not rule out a...

Newsquawk10 hours ago
Amazon.com IncAMZN.US+23

Capital One (COF) reportedly concerned about AI costs rising via cloud comput...

Capital One (COF) reportedly concerned about AI costs rising via cloud computing relationship with AWS (AMZN) and...

Newsquawk10 hours ago
United StatesUSD+15

Russia's President Putin says US President Trump is making frank efforts to e...

Russia's President Putin says US President Trump is making frank efforts to end the conflict in Ukraine. Russian...

Newsquawk10 hours ago
newsquawk_0a887ee5-f68f-4433-9fea-5ed772e4d54f_ac6ab65d.webp
United KingdomGBP+11

UK CBI Distributive Trades* (Dec) -44.0 (Prev. -32.0)

UK CBI Distributive Trades (Dec) -44.0 (Prev. -32.0) * Traders are closely monitoring the energy sector amid...

Newsquawk10 hours ago
newsquawk_85a06908-1fc3-4b55-a730-a08d41149bae_049acc4b.webp
United StatesUSD+19

Ukraine has hit Russian shadow fleet tanker in the Mediterranean sea for the ...

Ukraine has hit Russian shadow fleet tanker in the Mediterranean sea for the first time, according to Reuters...

Newsquawk10 hours ago
newsquawk_52fe2e80-2a92-450b-bbdc-e59c9ea24b06_d52b7045.webp
United StatesUSD+20

China Cabinet meeting said it should consolidate positive trend economy and p...

China Cabinet meeting said it should consolidate positive trend economy and prevent major accidents in production,...

Newsquawk10 hours ago

EU Session

newsquawk_1b34c551-cc98-4528-9282-86c59ce6ad88_b45bb9e2.webp
EU SessionHighlighted+2
9 hours ago

[MARKET UPDATE] Crude trims earlier losses and moves into the green despite a...

[MARKET UPDATE] Crude trims earlier losses and moves into the green despite a lack of newsflow and as traders...

United StatesUSD+14

"Iran's Judiciary on Protests: We Will Show No Mercy", according to Al Arabiya

"Iran's Judiciary on Protests: We Will Show No Mercy", according to Al Arabiya Iran's Judiciary has vowed no mercy...

Newsquawk9 hours ago
Manchester United PlcMANU.US+2

Manchester United (MANU) sack Ruben Amorim as head coach

Manchester United (MANU) sack Ruben Amorim as head coach Manchester United (MANU) have dismissed Ruben Amorim as...

Newsquawk9 hours ago
Prudential PLCICICI Bank Ltd+7

ICICI Bank (ICICIBC IS) plans to maintain majority stake in ICICI Prudential ...

ICICI Bank (ICICIBC IS) plans to maintain majority stake in ICICI Prudential Asset Management (ICICIAMC IS)...

Newsquawk9 hours ago
newsquawk_d20ab33c-94fe-4733-b5e8-153a1c5a0935_5d2bea90.webp
GermanyEU Session+4

German GfK Consumer Sentiment (Jan) -26.9 vs. Exp. -23.2 (Prev. -23.2

German GfK Consumer Sentiment (Jan) -26.9 vs. Exp. -23.2 (Prev. -23.2, Rev. -23.4) Traders are closely monitoring...

Newsquawk9 hours ago
newsquawk_bd0083e5-48e3-4e55-a1a6-4be107b887a4_43244a26.webp
USDJapan+27

BoJ Governor Ueda (post-policy press conference) says Japan's economy is reco...

BoJ Governor Ueda (post-policy press conference) says Japan's economy is recovering moderately, albeit with some...

Newsquawk9 hours ago
newsquawk_768599e1-a757-44ee-bf91-40aa51e73fdb_9d9c67bd.webp
Google IncMicrosoft Corp+19

The first phase of a Nanto data centre cluster would have 400-megawatt power ...

The first phase of a Nanto (?? CH) data centre cluster would have 400-megawatt power capacity, which would be...

Newsquawk9 hours ago
AustraliaBlueScope Steel Ltd+4

BlueScope Steel (BSL AT) reportedly received a bid from an Australian and US ...

BlueScope Steel (BSL AT) reportedly received a bid from an Australian and US consortium at AUD 30/shr BlueScope...

Newsquawk9 hours ago
United KingdomImportant+12

UK PSNB Ex Banks GBP (Nov) 11.653B GB vs. Exp. 10.0B GB (Prev. 17.434B GB

UK PSNB Ex Banks GBP (Nov) 11.653B GB vs. Exp. 10.0B GB (Prev. 17.434B GB, Rev. 21.189B GB) Traders are closely...

Newsquawk9 hours ago
SwedenEurope+9

Swedish Manufacturing Confidence* (Dec) 103.8 (Prev. 100.9)

Swedish Manufacturing Confidence (Dec) 103.8 (Prev. 100.9) * Traders are closely monitoring the energy sector amid...

Newsquawk9 hours ago
TurkeyAsia+5

Turkish Consumer Confidence* (Dec) 83.5 (Prev. 85.0)

Turkish Consumer Confidence (Dec) 83.5 (Prev. 85.0) * Traders are closely monitoring the energy sector amid...

Newsquawk10 hours ago
newsquawk_39c8cd70-e0cd-45ea-99e0-cfc37e47bbf3_17f66f43.webp
NorwayEU Session+3
10 hours ago

Norwegian Reg'd Unemployment NSA* (Dec) 2.1% vs. Exp. 2.2% (Prev. 2.1%)

Norwegian Reg'd Unemployment NSA (Dec) 2.1% vs. Exp. 2.2% (Prev. 2.1%) * Traders are closely monitoring the energy...

United StatesUSD+11

UK Trade Minister Bryant confirms a hack of Government data

UK Trade Minister Bryant confirms a hack of Government data UK Trade Minister Bryant confirms a significant data...

Newsquawk10 hours ago
GeopoliticalImportant+2

China's Foreign Ministry on Japanese official talking about nuclear arms

China's Foreign Ministry on Japanese official talking about nuclear arms, says if the reports are true, then the...

Newsquawk10 hours ago
HungaryEurope+4

Hungarian Gross Wages YY (Oct) 8.7% (Prev. 9.5%)

Hungarian Gross Wages YY (Oct) 8.7% (Prev. 9.5%) Traders are closely monitoring the energy sector amid fluctuating...

Newsquawk10 hours ago
newsquawk_127cff4f-fe5b-4e36-834e-0d8049718af7_13b99c23.webp
United StatesUSD+17

Belarus says "We are preparing to start the combat shift of the Russian Orysh...

Belarus says "We are preparing to start the combat shift of the Russian Oryshnik missile system", via Al Arabiya...

Newsquawk10 hours ago
newsquawk_a17e3c42-ccb4-4383-9b22-b2f0249c345a_292e3009.webp
FranceEU Session+3

French Producer Prices MM (Nov) 1.1%

French Producer Prices MM (Nov) 1.1% Traders are closely monitoring the energy sector amid fluctuating oil prices....

Newsquawk10 hours ago
newsquawk_96137892-2401-4723-a095-e4e46782fd71_4a800785.webp
ImportantEU Session+2

China's Commerce Ministry has launched an investigation into some rubber prod...

China's Commerce Ministry has launched an investigation into some rubber products from the US, South Korea and the...

Newsquawk10 hours ago